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Virome

Product Introduction

The viral metagenome, also known as the virome, is a new branch of science that has emerged based on the theory of metagenomics, in conjunction with existing virology and molecular biology technologies. The virome transcends the limitations of traditional technical methods by directly taking the genetic material of all viruses present in an environment or tissue as its subject of study. It can rapidly and accurately identify all viral components within a sample, serving as a powerful tool for discovering new viruses, studying viral community structure and diversity, and monitoring viral mutations and evolution. It plays a crucial role in virus discovery, tracing the origins of viruses, and microbial early warning systems.

Trends For the future Research In Virome

The importance of virome have been increasingly recognized, both the number and quality of related publications have increased profoundly in recent years targeting samples such as soil, water and human body.

Important Research Papers In Recent Years

Articles	Journals	Year
The evolutionary history of vertebrateRNA viruses	Nature	2018
Marine DNA Viral Macro-and Microdiversity from Pole to Pole	Cell	2019
The stepwise assembly of the neonatal virome is modulated by breastfeeding	Nature	2020
Breastfeeding influences the neonatal virome	Nature	2021
Cryptic and abundant marine viruses at the evolutionary origins of Earth’s RNA virome	Science	2022
Wastewater sequencing reveals community and variant dynamics of the collective human virome	Nature Communications	2023

The Number of Articles in the Virome Continues to Rise, and Unknown Fields are Waiting for Global Researchers to Explore, Making the Virome a Future Research Hotspot.

Virome-related articles statistics (based on PubMed)

Virus Enrichment

Viruses are ubiquitous, yet their enrichment remains challenging across various samples including human, animal, plant, marine, and soil due to their small genomes, low nucleic acid content, and susceptibility to host interference during processing. This poses a significant obstacle for the study of Viral metagenomics. Magigene has developed two efficient virus enrichment strategies to assist researchers in overcoming these challenges.

Ultracentrifugation: Pre-filtered samples are subjected to sucrose density gradient ultracentrifugation for over 24 hours for selective virus particles collection.

VirOne^® competitive precipitation method: VirOne^® competitive precipitation kit was developed by Magigene, which competitively binds and neutralizes the surface charges of water molecules, forcing the VLPs component to precipitate from the solution, thereby the viral particles can be precipitated rapidly by bench top centrifuge.

Both approaches have been proven to be effective and reliable through extensive tests. For further information, please consult our local marketing and sales personnel.

Technical parameters

Product	Sequencing Platform	Data Volume
Virome	NovaSeq PE150	10 G raw data

Product Advantages

Efficient and Comprehensive Sample Preprocessing Methods:The selection of multiple viral nucleic acid enrichment methods (such as ultracentrifugation or precipitation), allowing your project to balance quality, cycle, and cost.
Comprehensive Virus Analysis Strategy:The most comprehensive viromics analysis method tool, accurately exploring the unknown world of viruses.
Customized Virus High-end Personality Analysis:The top-notch virus group student information development team customizes virus omics personality analysis.

Analysis process

(1)Virome(DNA) analysis flowchart

(2)Virome(RNA) analysis flowchart

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